|
Area |
Focus |
|
Natural Product Chemistry |
Isolation, purification, crystallization, and structural elucidation of bioactive compounds |
|
Cancer Chemoprevention |
Antiproliferative effects, apoptosis & autophagy pathway mechanisms |
|
Food Chemistry |
Bioactive phytochemicals in fruits and vegetables |
|
Phyto-Pharmacology |
Hepatoprotective, anti-diabetic, anti-inflammatory, and antioxidant studies |
|
Nanomedicine |
Polymeric nanoparticles for encapsulation and delivery of plant extracts |
Biological Assays & Techniques
|
Category |
Specific Techniques |
|
In Vitro |
Antimicrobial, anticancer (cell lines: HeLa, EAC, HepG2, PC3), cytotoxicity (brine shrimp, MTT), antioxidant (DPPH, ABTS, ESR), anti-inflammatory |
|
In Vivo |
Hepatoprotective, anti-diabetic (streptozotocin-induced), analgesic, CNS depressant, anti-diarrheal, toxicological (sub-acute, acute) |
|
Molecular |
Western blot, apoptosis assays, cell culture, histopathology, biochemical analysis (hematological, serum enzymes) |
Key Instrumentation Handled
|
Instrument |
Experience Level |
|
Chromatography |
HPLC, Prep-HPLC, LC-MS, UPLC-MS/MS, GC-MS, Column Chromatography (Silica, Sephadex LH-20), TLC, Flash Chromatography |
|
Spectroscopy |
1D & 2D NMR, LC-NMR, Mass Spectroscopy (ESI, EI), UV-VIS, IR |
|
Other |
Rotary Evaporator, Soxhlet Extractor, Fermenter, Centrifuge, Lyophilizer (Freeze Dryer), Laminar Air Flow, Microtome, pH Meter |
Key Software Skills
- Microsoft Office Suite (Word, Excel, PowerPoint)
- Statistical Analysis (ANOVA, SPSS, GraphPad Prism)
- EndNote (Reference Management)
- Molecular Docking (basic)
Key Professional Certifications & Training
|
Training |
Topic |
Institution |
Year |
|
Advanced Training |
HPLC & NMR Analysis |
Centre for Phytochemistry, Southern Cross University, Australia |
2002–2004 |
|
Workshop |
EndNote for Thesis Writing |
Southern Cross University, Australia |
2003 |
|
Certification |
Data Meta-analysis for Review Papers |
Dammam University, KSA |
2018 |
|
Course |
Food & Genetically Modified Food Production |
Jeju National University, South Korea |
2009 |
Key Professional Experience (Non-Academic)
|
Position |
Organization |
Responsibilities |
Period |
|
Lab Demonstrator |
Complementary Medicine Dept., Southern Cross University, Australia |
Chemistry lab instruction |
2001–2004 |
|
Research Associate |
Centre for Phytochemistry & Pharmacology, Southern Cross University, Australia |
NMR, LC-MS, HPLC, GC-MS analysis |
2002–2004 |
|
A-Grade Pharmacist |
Pharmaceutical Industry (Bangladesh) |
Production & Quality Control sections |
Short-term |
- Natural products based new drug discovery
- Clinical studies of well-known medicinals plants of Bangladesh
- Development of High-Performance Liquid Chromatographic (HPLC) methods for analysis of medicinal extracts
- Ethno-pharmacology and
- Phytochemistry
- Structural Biology
- RNA Structure Determination through NMR
- Enzyme kinetics
- 3 Dimensional Quantitative Structure Activity Relationship Studies
- Pharmacological research and Chronic toxicological studies
- Clinical Microbiology
Medicinal Chemistry
Natural Product Chemistry
- Clinical and Hospital Pharmacy
- Clinical and Basic research of Pharmacology
- Clinical and Hospital Microbiology
- Public Health
- Studies on the antioxidant, cytotoxic, antimicrobial, antidiabetic, antinociceptive and anti-inflammatory activities of Bangladeshi medicinal plants.
- Isolation and characterization of bioactive compounds from Bangladeshi medicinal plants which involves various chromatographic methods with advanced spectrophotometric analysis.
- Isolation of endophytic fungi from fresh medicinal plants of Bangladesh followed by their extraction and isolation of various bioactive compounds.
- Evaluation of the role of selected molecules to improve vascular dysfunction in cardiovascular diseases using a combination of in-silico, in vitro, in vivo and biomolecular techniques
- Clinical Pharmacology
- Cancer Pharmacology
- Phytopharmacology
- Drug discovery from natural sources
- Public health
- Synthetic chemistry
- Pharmacology
- Bioinformatics
- Public health
- Study of prevalence and genomic landscape of multidrug resistant pathogenic bacteria in clinical isolates obtained from patients.
- Epidemiological studies on different categories of diseases prevailing among Bangladeshi population and assessment of knowledge, attitude and practice of Bangladeshi population regarding various issues related to public health.
- Prescription behavior and evaluation of clinical parameters of patients suffering from various communicable and non-communicable diseases.
- Studies on in vitro pharmacological activities like antioxidant, cytotoxic, antimicrobial etc. of Bangladeshi medicinal plants.
- Pharmaceutical Sciences
- In silico drug design
- Material Chemistry
- Public health
- Natural products:
- Evaluation of phytochemical and pharmacological properties of medicinal plants of Bangladesh and their associated endophytic fungi as well as isolation of bioactive compounds from those natural sources.
- Microbiology:
- Investigating microbial prevalence in biological samples and the antimicrobial resistance pattern.
- Public Health:
- Studying knowledge, attitude, and practice of Bangladeshi population regarding various public health related issues.
- Assessment of prescribing trends of drugs and clinical parameters of patients during different types of communicable and non-communicable diseases.
- Analyzing prevalence of risk factors for various types of diseases among Bangladeshi population.
Primary Research Interest: Diabetology & Insulin Resistance, ROS, Ion Channels, Cardiology, Cell Signaling & MMDA
Secondary Research Interest: Public Health
- Phytochemistry & Public health
- Microbiology and Clinical survey
- Pharmacology and Toxicological studies
- Phytopharmacology
- Anticancer drug evaluation
- Computational Biology
