A/2, Jahurul Islam Avenue
Jahurul Islam City, Aftabnagar
Dhaka-1212, Bangladesh
Prof. Hossain was awarded a prestigious fellowship from the Science and Technology Agency (STA) of the Japanese government in 1994 and placed at the National Institute of Health Science (NIHS) in Japan to complete his post-doctoral studies. Later in 1995, he was also awarded a Human Science Foundation post-doctoral fellowship for three years.
In 1996, he embarked on a teaching career as an Assistant Professor in the Pharmacy Department at Dhaka University, later being promoted to Associate Professor in 2000.
In the same year, he was invited to work as a Visiting Scientist at the National Center for Natural Products Research (NCNPR) of the University of Mississippi, USA, where he collaborated with well-renowned F.A.P. Barnard Distinguished Professor Alice M. Clark’s research group. During his tenure in the USA, Prof. Hossain made seminal contributions to federally funded anticancer research projects, pioneering the discovery and characterization of novel antitumor agents that effectively inhibit the hypoxia-inducible survival factor (HIF-1) in breast tumor cells. Dr. Hossain discovered a series of dineolignans, manassantins, from an aquatic plant as the most potent inhibitor of HIF-1α ever known to date.
Notably, he unveiled a potent series of dineolignans, manassantins, from an aquatic plant, marking an unparalleled advancement in HIF-1α inhibitor research. His research was underscored by two US patents and numerous peer-reviewed publications, with one receiving the Jack L. Beal Award by the American Society of Pharmacognosy for being the best manuscript published in 2004 in the flagship journal, the Journal of Natural Products.
After returning from the USA, Dr. Hossain joined Manarat International University as an Associate Professor and attained the rank of Professor within a short span. In January 2009, he joined East West University as a Professor. He has since served the university in various capacities, including as the Dean of the Faculty of Sciences and Engineering, Chairperson of the Department of Pharmacy, and member of the Syndicate and the Academic Council.
In recognition of his outstanding academic research contributions, he received a Certificate of Excellence from East West University in 2009. Furthermore, he was honored with the Bangladesh Education Leadership Awards in 2019 for the Best Professor in Pharmacy Studies by the World Education Congress.
Prof. Hossain is currently working on natural-products-based drug discovery for non- alcoholic steatohepatitis from medicinal plants of Bangladesh. His contributions to new drug discovery and extensive research experience make him a respected figure in the field.
KEY ACHIEVEMENTS
Dr. Hossain boasts an extensive background as both an academician and a scientist, encompassing 28 years of dedicated involvement in teaching and research.
A consistent record of exceptional productivity underscores their remarkable history. Dr. Hossain has been pivotal in numerous therapeutic projects that delivered successful new drug candidates. He is experienced in facilitating multiple collaborations to evaluate and implement cutting-edge technologies in Natural-Product Drug Discoveries. Throughout his career, Dr. Hossain has imparted knowledge through over 25 years of teaching graduate and undergraduate courses at the university level in Medicinal Chemistry, Analytical Chemistry, Pharmacology, Pharmacognosy, etc., and supervised graduate students in their research.
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Journal of Asian Natural Products Research (2023) 25 (3), 252-263
GNN Sultana, A Das, K Akhtaar, CF Hossain, MA Islam
Bioresearch Communications (2023) 9 (1), 1177-1179
Screening and Characterization of L-asparaginase Producing Bacterial Strains from the Soil in Bangladesh
CF Hossain, TN Nijhum, M Imam, M Kabir
Journal of Advances in Microbiology (2022) 81-92
Fluorescence Resonance Energy Transfer Based Biosensor from Thermophilic Bacterial Periplasmic Binding Protein to Measure Branched-chain and Aromatic Amino Acids
M Kabir, M Imam, CF Hossain, GNN Sultana
Journal of Advances in Biology & Biotechnology (2022) 25 (6), 24-38
Arjunolic acid downregulates elevated blood sugar and pro-inflammatory cytokines in streptozotocin (STZ)-nicotinamide induced type 2 diabetic rats
K Aamir, HU Khan, CF Hossain, MR Afrin, PR Jusuf, I Waheed, G Sethi, ...
Life sciences (2022) 289, 120232
“Le Carbone prevents liver damage in non-alcoholic steatohepatitis-hepatocellular carcinoma mouse model via AMPKα-SIRT1 signaling pathway activation”.
Afrin, M.R., Arumugam, S., Pitchaimani, V., Karuppagounder V., Thandavarayan, R.A., Harima, M., Hossain, C.F., Suzuki, K., Sone, H., Matsubayashi, Y., Watanabe, K.
Heliyon (2021), 7: e05888.
“Inhibitory Activity of Extract, Fractions, and Compounds from Zingiber montanum Rhizomes on the Migration of Breast Cancer Cells”.
Al-Amin, M., Eltayeb, N.M., Hossain, C.F., Khairuddean, M., Rahiman, S.S.F.
Planta Medica (2020), 86(06), 387-394.
Patents
Certificate of Excellence in recognition of his outstanding academic research contribution in 2009 from East West University